Professor Monty Mythen

Monty Mythen

Professor Monty Mythen


  • Smiths Medical Professor of Anaesthesia and Critical Care at University College London
  • Director of The UCL Discovery Lab at The London 2012 Olympic legacy Institute of Sport Exercise and Health
  • Editor-in-Chief Perioperative Medicine Journal
  • Elected Council Member Royal College of Anaesthetists
  • Chair of The Board and Council Member of the National Institute of Academic Anaesthesia
  • Editorial board member: British Journal of Anaesthesia
  • Critical Care and Co-Chairman of Evidence Based Peri-operative Medicine (EBPOM)


Recent Grants

  • National Institute of Health Research (NIHR) Research for Patient Benefit (RfPB) programme. PB-PG-0906-11426 - A randomised controlled trial of the utility of Cardiopulmonary Exercise (CPX) Testing for preoperative risk stratification to guide perioperative care and thereby reduce postoperative morbidity. Awarded: 01/07/2007 (6 years) £250,000.00. Co-applicants Dr Michael GROCOTT, Professor Mervyn SINGER, Dr Geoff BELINGAN, Mr Al WINDSOR, Mr Hassan MUKTHAR, Mr Ayo OSHOWA, Prof Michael MYTHEN
  • NIHR Health Technology Assessment Programme Project Ref: 07/52/03 ISRCTN 17386141 (International Standard Randomised Controlled Trial Number) URL of this project on the Controlled Website: CALORIES (Early Enteral Vs Parenteral Nutrition in the Critically Ill) Awarded: 01/07/2008 (5 years) £1,362,835.00. Principal Investigator Prof Michael MYTHEN Co-applicants Katherine ROWAN, Geoff BELLINGAN, Richard BEALE, Richard HOWARD, Alistair FORBES
  • Hutchinson Technologies Muscle Near Infrared Spectroscopy and Outcome Following Cardiac Surgery. Awarded: 01/12/2005 £80,000.00 Principal Investigator Prof Michael MYTHEN, Co-applicants Mark HAMILTON, Julie SAUNDERS
  • Smiths Medical Award Hypoxia Research at University College London (UCL) and Everest Expedition. Awarded: 01/08/2006 £3,270,845.00 and Awarded: 01/08/2008 (5 years) £1,500,000 Principal Investigator Prof Michael MYTHEN
  • BOC Inspire Award Hypoxia Research on Everest. Awarded: 01/07/2006 £300,000.00 and finished in 2009; Co-Principal Investigator Michael GROCOTT, Hugh MONTGOMERY, Prof Michael MYTHEN
  • National Institute for Health Research - Research for Patient Benefit PB-PG-0609-18262: The effect of neo-adjuvant chemotherapy on exercise capacity and outcome following upper gastrointestinal cancer surgery. Awarded: 01/06/2009 (4 years) £250,000.00 Co-Principal Investigator Mike GROCOTT, Prof Michael MYTHEN
  • Frances and Augustus Newman Foundation Systematic Reviews of Perioperative Risk and Outcome Measures. Awarded: 01/01/2008 upto 2011 (3 years) £47,510.00 Co-Principal Investigator Dr Judith HULF, Dr Michael GROCOTT, Professor Michael MYTHEN, Professor Rosalind RAINE, Dr John BROWNE, Dr Jan VAN DER MEULEN, Prof Kathy ROWAN.
  • Deltex Medical Caudwell Xtreme Everest. Hypoxia Research and Education. Awarded: 15/03/2007 £150,000.00 Co-Principal Investigator Dr Michael GROCOTT, Professor Michael MYTHEN.
  • National Institute of Health Research UCLH/UCL Comprehensive Biomedical Research Centre Surgical Outcomes Research Centre (SOuRCe). Awarded: 01/01/2007 upto 2012 £250,000.00 Co-applicant Dr Michael GROCOTT, Professor Rosalind RAINE, Mr Hiten PATEL, Mr Al WINDSOR, Mr Fares HADDAD, Prof Michael MYTHEN.

    Total for all Records $10,229,100.00 (£5,961,190.00)


UCL Research Publication Services reports 325 scholarly articles and calculates my h-index to be 29-33 (33 Scopus; 29 Web of Science) as of May 22nd 2015.

Pubmed records 174 original articles as of May 22 2015.

Recent publications (2013-15)

  • Ashby E, Matejowsky C, Mythen MG, Haddad FS, Grocott MP. How efficient is patient discharge following lower limb arthroplasty? Perioperative medicine. 2015;4:5.
  • Simpson JC, Moonesinghe SR, Grocott MP, Kuper M, McMeeking A, Oliver CM, et al. Enhanced recovery from surgery in the UK: an audit of the enhanced recovery partnership programme 2009-2012. British journal of anaesthesia. 2015.
  • Navarro LH, Bloomstone JA, Auler JO, Jr., Cannesson M, Rocca GD, Gan TJ, et al. Perioperative fluid therapy: a statement from the international Fluid Optimization Group. Perioperative medicine. 2015;4:3.
  • Miller TE, Roche AM, Mythen M. In reply: Fluid management issues in Enhanced Recovery After Surgery and Canadian Anesthesiologists' Society standards. Canadian journal of anaesthesia = Journal canadien d'anesthesie. 2015.
  • Edwards MR, Sultan P, Gutierrez Del Arroyo A, Whittle J, Karmali SN, Moonesinghe SR, et al. Metabolic dysfunction in lymphocytes promotes postoperative morbidity. Clinical science. 2015.
  • Mythen MG. Does gastric tonometry-guided therapy reduce total mortality in critically ill patients? Critical care. 2015;19(1):172.
  • Minto G, Mythen MG. Perioperative fluid management: science, art or random chaos? British journal of anaesthesia. 2015;114(5):717-21.
  • Martin DS, Cobb A, Meale P, Mitchell K, Edsell M, Mythen MG, et al. Systemic oxygen extraction during exercise at high altitude. British journal of anaesthesia. 2015;114(4):677-82.
  • Harvey SE, Parrott F, Harrison DA, Mythen M, Rowan KM. The CALORIES trial: statistical analysis plan. Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine. 2014;16(4):248-54.
  • Miller TE, Roche AM, Mythen M. Fluid management and goal-directed therapy as an adjunct to Enhanced Recovery After Surgery (ERAS). Canadian journal of anaesthesia = Journal canadien d'anesthesie. 2015;62(2):158-68.
  • Mythen MG. Spread and adoption of enhanced recovery from elective surgery in the English National Health Service. Canadian journal of anaesthesia = Journal canadien d'anesthesie. 2015;62(2):105-9.
  • Raghunathan K, Murray PT, Beattie WS, Lobo DN, Myburgh J, Sladen R, et al. Choice of fluid in acute illness: what should be given? An international consensus. British journal of anaesthesia. 2014;113(5):772-83.
  • Kellum JA, Mythen MG, Shaw AD. The 12th consensus conference of the Acute Dialysis Quality Initiative (ADQI XII). British journal of anaesthesia. 2014;113(5):729-31.
  • Edwards MR, Mythen MG. Fluid therapy in critical illness. Extreme physiology & medicine. 2014;3:16.
  • Harvey SE, Parrott F, Harrison DA, Bear DE, Segaran E, Beale R, et al. Trial of the route of early nutritional support in critically ill adults. The New England journal of medicine. 2014;371(18):1673-84.
  • Wade DM, Hankins M, Smyth DA, Rhone EE, Mythen MG, Howell DC, et al. Detecting acute distress and risk of future psychological morbidity in critically ill patients: validation of the intensive care psychological assessment tool. Critical care. 2014;18(5):519.
  • Chawla LS, Ince C, Chappell D, Gan TJ, Kellum JA, Mythen M, et al. Vascular content, tone, integrity, and haemodynamics for guiding fluid therapy: a conceptual approach. British journal of anaesthesia. 2014;113(5):748-55.
  • Goldstein S, Bagshaw S, Cecconi M, Okusa M, Wang H, Kellum J, et al. Pharmacological management of fluid overload. British journal of anaesthesia. 2014;113(5):756-63.
  • Hoste EA, Maitland K, Brudney CS, Mehta R, Vincent JL, Yates D, et al. Four phases of intravenous fluid therapy: a conceptual model. British journal of anaesthesia. 2014;113(5):740-7.
  • Rosner MH, Ostermann M, Murugan R, Prowle JR, Ronco C, Kellum JA, et al. Indications and management of mechanical fluid removal in critical illness. British journal of anaesthesia. 2014;113(5):764-71.
  • Cannesson M, Ani F, Mythen MM, Kain Z. Anaesthesiology and perioperative medicine around the world: different names, same goals. British journal of anaesthesia. 2015;114(1):8-9.
  • Miller TE, Mythen M. Successful recovery after major surgery: moving beyond length of stay. Perioperative medicine. 2014;3:4.
  • Moonesinghe SR, Harris S, Mythen MG, Rowan KM, Haddad FS, Emberton M, et al. Survival after postoperative morbidity: a longitudinal observational cohort study. British journal of anaesthesia. 2014;113(6):977-84.
  • Wade DM, Brewin CR, Howell DC, White E, Mythen MG, Weinman JA. Intrusive memories of hallucinations and delusions in traumatized intensive care patients: An interview study. British journal of health psychology. 2014.
  • Siervo M, Riley HL, Fernandez BO, Leckstrom CA, Martin DS, Mitchell K, et al. Effects of prolonged exposure to hypobaric hypoxia on oxidative stress, inflammation and gluco-insular regulation: the not-so-sweet price for good regulation. PloS one. 2014;9(4):e94915.
  • Myburgh JA, Mythen MG. Resuscitation fluids. The New England journal of medicine. 2013;369(25):2462-3.
  • Martin DS, Gilbert-Kawai E, Levett D, Mitchell K, Kumar Bc R, Mythen MG, et al. Xtreme Everest 2: unlocking the secrets of the Sherpa phenotype? Extreme physiology & medicine. 2013;2(1):30.
  • Moonesinghe SR, Mythen MG, Das P, Rowan KM, Grocott MP. Risk stratification tools for predicting morbidity and mortality in adult patients undergoing major surgery: qualitative systematic review. Anesthesiology. 2013;119(4):959-81.
  • Vincent JL, Kellum JA, Shaw A, Mythen MG. Should hydroxyethyl starch solutions be totally banned? Critical care. 2013;17(5):193.
  • Myburgh JA, Mythen MG. Resuscitation fluids. The New England journal of medicine. 2013;369(13):1243-51.
  • Gillies MA, Habicher M, Jhanji S, Sander M, Mythen M, Hamilton M, et al. Incidence of postoperative death and acute kidney injury associated with i.v. 6% hydroxyethyl starch use: systematic review and meta-analysis. British journal of anaesthesia. 2014;112(1):25-34.
  • Van Der Linden P, James M, Mythen M, Weiskopf RB. In response. Anesthesia and analgesia. 2013;117(2):530-1.
  • Martin DS, Gilbert-Kawai ET, Meale PM, Fernandez BO, Cobb A, Khosravi M, et al. Design and conduct of 'Xtreme Alps': a double-blind, randomised controlled study of the effects of dietary nitrate supplementation on acclimatisation to high altitude. Contemporary clinical trials. 2013;36(2):450-9.
  • Nolan JP, Mythen MG. Hydroxyethyl starch: here today, gone tomorrow. British journal of anaesthesia. 2013;111(3):321-4.
  • Butterworth JFt, Mythen MG. Should "normal" saline be our usual choice in normal surgical patients? Anesthesia and analgesia. 2013;117(2):290-1.
  • Grocott MP, Dushianthan A, Hamilton MA, Mythen MG, Harrison D, Rowan K, et al. Perioperative increase in global blood flow to explicit defined goals and outcomes after surgery: a Cochrane Systematic Review. British journal of anaesthesia. 2013;111(4):535-48.
  • Wade D, Hardy R, Howell D, Mythen M. Identifying clinical and acute psychological risk factors for PTSD after critical care: a systematic review. Minerva anestesiologica. 2013;79(8):944-63.